bio1 Immune checkpoint Immune checkpoint : Cytotoxin T cell 수용체(receptor) PD1에 리간드(ligand) PDL1가 결합하여 Cytotoxin T cell을 비활성화 시킨다. Usage - TMB : tumor mutation burden, 종양 돌연변이 빈도 - ICT : Immune checkpoint therapy - CD8 : cluter of differentiation 8 - TCR : T-cell receptor - PD1 : programmed cell death receptor 1 - PDL1 : programmed cell death receptor ligand 1 - CTLA4 : cytotoxic T-lymphocyte-associated antigen 4 - MHC.. 2021. 4. 8. 이전 1 다음